System font (?) disappearance

I’m having a weird issue… yesterday when I turned on my machine, the smallish light Arial-like font that shows up in many application dialogs is gone and replaced by a much larger bold font.

I didn’t get any errors and definitely didn’t delete any fonts. I ran a full virus sweep and didn’t catch anything either.

Here’s what WS_FTP Pro looks like now:

I’m using Linotype FontExplorer to manage my fonts, and I checked through there too to see if I’d deactivated something by mistake but no. Any ideas?

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